Lyme Disease usually responds very well to antibiotic therapy. The Lyme Disease Center recommends that oral antibiotic therapy be used for thirty days. If you are treated in the early stage of Lyme Disease with too short of an antibiotic course your blood tests may never become positive and the Lyme bacteria may still be present in the body. Even if you feel perfectly well, be sure to take the full course of medication so that you can prevent moving into the Early Disseminated Stage or the Late/Chronic Stage of Lyme Disease.

The medications that are most often prescribed are as follows:

  • Treatment for Early Localized is oral amoxicillin, tetracycline, doxycyline, penicillin, cenfuroxime axetil, or erthromycin if allergic to the others.
  • Treatment for Early Disseminated is a prolonged high dose of oral amoxicillin, tetracycline, or doxycyline
  • Treatment for Late or the Chronic Stage is an intravenous high dose penicillin or a third generation cephalosporin.

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